In the second edition of best-selling textbook Oral Microbiology and Immunology, an international panel of editors presents an in-depth, comprehensive understanding of the oral ecosystem and its role in human health and disease. Written specifically for dental students, dental practitioners, and healthcare professionals, Oral Microbiology and Immunology cohesively details the ecology, virulence, molecular biology, and immunogenicity of oral bacteria, viruses, and fungi and examines their interfaces with host cells and secretions.

This new edition addresses the technological and conceptual advances that have increased our understanding of the etiology of oral diseases and the nature of pathogenic mechanisms and the host response, including:

• Genome sequencing of a bacterium or a community of bacteria.
• Knockout mice deficient in specific components of both the innate and adaptive immune systems.
• High-resolution and 3D imaging techniques of communities growing in biofilms and the intimate interactions between microbes and host cells.